Webb26 feb. 2024 · R-loops are three-stranded DNA/RNA hybrids that form by the annealing of the mRNA transcript to its coding template while displacing the non-coding strand. While … Webb15 sep. 2024 · Over 40 RBPs responsible for virtually all aspects of RNA metabolism, from synthesis to degradation, are recurrently mutated in cancer, and just over a dozen are …
Roles of RNA-binding proteins in immune diseases and cancer
WebbMost importantly, low-expression levels of PIWIL1 (P=0.009), PIWIL2 (P<0.0001), and PIWIL4 (P=0.0065) were significantly associated with worse overall survival in renal cell carcinoma (RCC) patients. Our results suggest the involvement of PIWIL genes and piR-823 in RCC pathogenesis, and indicate PIWIL1, PIWIL2, and PIWIL4 as potential prognostic … Webb7 apr. 2024 · RNA-binding proteins (RBPs) are essential for tumorigenesis, immune evasion, invasion, migration and metastasis, hence promising drug targets in cancer … showdisassemblingpartsquantity
IJMS Free Full-Text R-Loops and R-Loop-Binding Proteins in …
Webb1 nov. 2024 · Probing RNA-Binding Proteins in Cancer. Cancer Discovery ( IF 39.397 ) Pub Date : 2024-11-01 , DOI: 10.1158/2159-8290.cd-nd2024-0115. American Association for … Webb1 nov. 2024 · Using large-scale quantitative methods combined with systems biology, 1542 genes have been identified as RBPs, representing 7.5% of all protein-coding genes in … Webb12 apr. 2024 · Deconvoluting this RNA interactome, including the interacting partners, the nature of the interaction, and dynamic changes of these interactions in malignancies has … showdinner